Thiol isomerases negatively regulate the cellular shedding activity of ADAM17

Keyphrases

• ADAM17 100%
• Adamalysin 10%
• Binding Studies 10%
• Cell Surface Receptor 10%
• Cell Surface Signaling 10%
• Cell-based 10%
• Conformational Change 10%
• CRISTAL 10%
• Disintegrin 10%
• Disulfide Bond 10%
• Disulfide Bond Pattern 20%
• Fragment Antibody 10%
• Isomerization 10%
• Metalloproteinases 10%
• Mitochondrial Reactive Oxygen Species (mtROS) 10%
• Negatively Regulate 100%
• Phorbol Ester 10%
• Proligand 10%
• Protein Disulfide Isomerase 10%
• Redox Environment 10%
• Redox Regulation 10%
• Regulatory Pathways 10%
• Relative Orientation 10%
• Sheddase Activity 10%
• Sheduling 100%
• Signaling Events 10%
• Soluble Form 10%
• Thiolase 100%

Biochemistry, Genetics and Molecular Biology

• ADAM17 100%
• Adamalysin 10%
• Binding Study 10%
• Conformational Change 10%
• Crystal Structure 10%
• Disintegrin 10%
• Disulfide Bond 30%
• Downregulation 10%
• Isomerase 100%
• Isomerization 10%
• Metalloendopeptidase 10%
• Metalloproteinase 10%
• Protein Disulfide-Isomerase 10%
• Sheddase 10%
• Thiol 100%

Pharmacology, Toxicology and Pharmaceutical Science

• Disintegrin 10%
• Disulfide Bond 30%
• Enzyme-Linked Immunosorbent Assay 10%
• Isomerase 100%
• Metalloproteinase 10%
• Phorbol Ester 10%
• Protein Disulfide Isomerase 10%
• Reactive Oxygen Metabolite 10%
• Receptor 10%
• Thiol 100%
• Tumor Necrosis Factor Alpha Converting Enzyme 100%