Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

Keyphrases

• Mitochondrial DNA mutation 100%
• Functional Consequences 100%
• Human Cancer 100%
• Somatic Alterations 40%
• Heteroplasmy 20%
• Apoptosis 20%
• Missense mutation 20%
• Energy Metabolism 20%
• Impact of Cancer 20%
• Cancer Origin 20%
• Mutational Mechanism 20%
• Sequencing Studies 20%
• Cancer mutations 20%
• Nuclear Genome 20%
• Control Energy 20%
• Strand Bias 20%
• Cancer Genome 20%
• Tumor Subtype 20%
• Sequence Content 20%
• Primates 20%
• Protein Truncation 20%
• Negative Selection 20%
• Mutagens 20%
• Homoplasmy 20%

Biochemistry, Genetics and Molecular Biology

• DNA Mutation 100%
• Mitochondrial DNA 100%
• Programmed Cell Death 20%
• Heavy Strand 20%
• Missense Mutation 20%
• Mitochondrial DNA Replication 20%
• Energy Metabolism 20%
• Homoplasmy 20%