Lysosome and cytoskeleton pathways are robustly enriched in the blood of septic patients: A meta-analysis of transcriptomic data

Keyphrases

• Meta-analysis 100%
• Cytoskeleton 100%
• Septic Patients 100%
• Sepsis 100%
• Lysosome 100%
• Transcriptomic Data 100%
• Human Sepsis 100%
• Messenger RNA Expression 66%
• Signaling Pathway 33%
• Messenger RNA (mRNA) 33%
• Patient Relatives 33%
• Protein-protein Interaction Network 33%
• Cell Adhesion Molecules 33%
• Expression Data 33%
• Whole Blood 33%
• Membrane Protein 33%
• Intensive Care Unit 33%
• Protease 33%
• Sepsis Patients 33%
• System Response 33%
• Immune Dysfunction 33%
• Biomarkers for Early Diagnosis 33%
• Blood System 33%
• LAPTM4B 33%
• RNA Activation (RNAa) 33%
• Spliceosome 33%
• SORT1 33%
• Cathepsin 33%
• Molecular Pathogenesis 33%
• Therapeutic Interventions 33%
• Key Regulatory Genes 33%
• Lysosome-associated Membrane Protein 1 (LAMP1) 33%
• Causes of Mortality 33%
• Lysosome Pathway 33%
• Microarray Assay 33%
• Acid Hydrolases 33%
• Activation Profile 33%

Biochemistry, Genetics and Molecular Biology

• Transcriptomics 100%
• Cytoskeleton 100%
• Lysosome 100%
• Messenger RNA 75%
• Mitogen-Activated Protein Kinase 25%
• Membrane Protein 25%
• Signal Transduction 25%
• Protein-Protein Interaction Networks 25%
• Protease 25%
• Locus Control Region 25%
• Acid Hydrolase 25%
• Spliceosome 25%
• Carboxypeptidase C 25%
• LAMP1 25%
• Cell Adhesion Proteins 25%

Immunology and Microbiology

• Cytoskeleton 100%
• Transcriptomics 100%
• Lysosome 100%
• Ribonucleic Acid 75%
• Cell Adhesion Proteins 25%
• Signal Transduction 25%
• Regulator Gene 25%
• Proteinase 25%
• Protease 25%
• LAMP1 25%
• Immune System Disorders 25%
• Protein-Protein Interaction Networks 25%
• Spliceosome 25%