TY - JOUR
T1 - Extending experimentation
T2 - oncology’s fading boundary between research and care
AU - Cambrosio, Alberto
AU - Keating, Peter
AU - Vignola-Gagné, Etienne
AU - Besle, Sylvain
AU - Bourret, Pascale
N1 - Funding Information:
A first version of this paper was presented at the Workshop on “Genomics as a health care strategy: Persons, practices, policies” (Institut Curie, Paris, April 14–15, 2016). We would like to thank the organizers of the Workshop, Simone Bateman and Dominique Stoppa-Lyonnet, for their kind invitation, and several participants for their critical remarks. We would also like to thank Jonathan Kimmel-man for sharing his views about bioethics, which are not represented in this paper. Research for this paper was made possible by grants from the Canadian Institutes of Health Research (CIHR MOP-133687), the Fonds de recherche du Québec Société et Culture (FRQSC SE-164195), and the French National Cancer Institute (INCa) (SHSESP14-002).
Funding Information:
This work was supported by the Canadian Institutes of Health Research [grant number MOP-133687]; Institut National Du Cancer [grant number SHSESP14-002]; Fonds de Recherche du Québec - Société et Culture [grant number FRQSC SE-164195].
Publisher Copyright:
© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2018/7/3
Y1 - 2018/7/3
N2 - Historians and social scientists view the distinction between research and care as diachronically and synchronically contingent, rather than transcendental, as is often the case in bioethics. Comparing how the notion of total care was used in the 1950s with present-day use of that same term by genomically informed oncology programs, the paper argues that the distinction between research and care needs: to be historicized, by examining its repeated emergence and re-definition, and the shifting relations between these two “ideal-typical” components; and to be problematized, by paying attention to the entities, practices, and institutions that are constitutive of the successive regimens that have punctuated oncology’s development. Shifting to contemporary activities, the paper examines how the recent massive injection of molecular biology and high-throughput genomic technologies in the field of oncology has been accompanied by a reshuffling of the research/care distinction, a process that is leading to new forms of “experimental care”.
AB - Historians and social scientists view the distinction between research and care as diachronically and synchronically contingent, rather than transcendental, as is often the case in bioethics. Comparing how the notion of total care was used in the 1950s with present-day use of that same term by genomically informed oncology programs, the paper argues that the distinction between research and care needs: to be historicized, by examining its repeated emergence and re-definition, and the shifting relations between these two “ideal-typical” components; and to be problematized, by paying attention to the entities, practices, and institutions that are constitutive of the successive regimens that have punctuated oncology’s development. Shifting to contemporary activities, the paper examines how the recent massive injection of molecular biology and high-throughput genomic technologies in the field of oncology has been accompanied by a reshuffling of the research/care distinction, a process that is leading to new forms of “experimental care”.
KW - clinical care
KW - clinical research
KW - genomics
KW - molecular tumor boards
KW - oncology
KW - total cancer care
UR - http://www.scopus.com/inward/record.url?scp=85052832057&partnerID=8YFLogxK
U2 - 10.1080/14636778.2018.1487281
DO - 10.1080/14636778.2018.1487281
M3 - Article
AN - SCOPUS:85052832057
SN - 1463-6778
VL - 37
SP - 207
EP - 226
JO - New Genetics and Society
JF - New Genetics and Society
IS - 3
ER -