Chromoproteins of the green fluorescent protein family: Properties and applications

M. A. Shkrob, A. S. Mishin, D. M. Chudakov, Yu A. Labas, K. A. Lukyanov

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The distribution in nature and the spectral and structural properties of chromoproteins of the green fluorescent protein (GFP) family and their differences from one another and other fluorescent proteins of this family are considered. Discussed in detail are practical applications of the chromoproteins and their mutant variants that have unique characteristics not found among natural proteins of the GFP family, such as far-red or photoconvertible fluorescence, a large Stokes shift, enhanced phototoxicity, etc.

Original languageEnglish
Pages (from-to)517-525
Number of pages9
JournalRussian Journal of Bioorganic Chemistry
Volume34
Issue number5
DOIs
StatePublished - Sep 2008
Externally publishedYes

Keywords

  • Fluorescent labeling
  • Nonfluorescent chromoprotein
  • Photoconversion
  • Photosensitizer
  • Red fluorescent protein
  • Structure of chromophore

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