TY - JOUR
T1 - Adverse drug reactions in the urinary tract
AU - Soomro, Naeem A.
AU - Neal, David E.
PY - 1998
Y1 - 1998
N2 - Drugs can cause adverse effects on the urinary tract by a local action, or as a result of systemic effects on the autonomic nervous system, or central nervous control of bladder emptying. Tiaprofenic acid and cyclophosphamide as its metabolite acrolein, for example, can cause haemorrhagic cystitis. Localised retroperitoneal fibrosis, from methysergide, for instance, can lead to hydronephrosis. Agents with anticholinergic actions, such as the tricyclic antidepressants, can result in urinary retention, whilst alpha-adrenoceptor antagonists may lead to stress incontinence in females.
AB - Drugs can cause adverse effects on the urinary tract by a local action, or as a result of systemic effects on the autonomic nervous system, or central nervous control of bladder emptying. Tiaprofenic acid and cyclophosphamide as its metabolite acrolein, for example, can cause haemorrhagic cystitis. Localised retroperitoneal fibrosis, from methysergide, for instance, can lead to hydronephrosis. Agents with anticholinergic actions, such as the tricyclic antidepressants, can result in urinary retention, whilst alpha-adrenoceptor antagonists may lead to stress incontinence in females.
UR - http://www.scopus.com/inward/record.url?scp=0032429748&partnerID=8YFLogxK
U2 - 10.1097/00012995-199812000-00001
DO - 10.1097/00012995-199812000-00001
M3 - Estudio breve
AN - SCOPUS:0032429748
SN - 0044-6394
SP - 735
EP - 738
JO - Adverse Drug Reaction Bulletin
JF - Adverse Drug Reaction Bulletin
IS - 193
ER -